Inkqubo yecwecwe emanzi yegranulation

Amacwecwe okwangoku yenye yeefom zedosi esetyenziswa kakhulu, enesiphumo esikhulu kunye nesona sisetyenziswa kakhulu.Inkqubo yemveli yegranulation emanzi iseyeyona nkqubo iphambili kwimveliso yamayeza.Ineenkqubo zokuvelisa ezivuthiweyo, umgangatho olungileyo wamasuntswana, ukusebenza kakuhle kwemveliso, kunye noxinzelelo lokubumba.Okuhle kunye nezinye izibonelelo, yeyona isetyenziswa kakhulu kwishishini lamayeza.

Inkqubo yokuvelisa amacwecwe anokuthi ahlulwe ngokubanzi ekuqhutyweni kwezinto eziluhlaza kunye nezincedisayo, ukulinganisa, ukuxubha, ukomisa, ukuxuba, i-tableting, i-coating, njl. kunye nokupakishwa ngumsila wePhoenix, kunokubonwa ukuba inkqubo yegranulation idlala indima ebalulekileyo kuyo yonke imveliso yethebhulethi, kodwa indlela yokwenza izinto ezithambileyo kunye nokufumana iigranules, ukuza kuthi ga ngoku kukho intsingiselo enzulu kakhulu kwiincwadi zokufunda ibhola, ukubamba nokuchithachitha” , Ayichazwanga.Ngokusekelwe kumava obuqu ombhali kwimveliso eyiyo, eli nqaku lihlalutya izinto ezininzi eziqhelekileyo ezichaphazela uzinzo lwenkqubo yegranulation emanzi yethebhulethi, kwaye iphakamisa amanyathelo olawulo afanelekileyo ukuqinisekisa umgangatho wokuveliswa kweziyobisi.

Unyango lwangaphambili lwemathiriyeli ekrwada

Izinto ezikrwada kunye nezincedisayo ngokubanzi kufuneka zicolwe kwaye zihlolwe phambi kokuxutywa okumanzi kunye nokuveliswa kwegranulation.Ezinye izinto ezingafanelekanga ezihlala zisenzeka kwinkqubo yokusetyenziswa kweepilisi, ezinjengokuxuba ukungalingani, ukwahlula, ukuncamathela okanye ukuchithwa, njl.Ukuba izinto eziluhlaza ziyi-scaly okanye i-crystals efana nenaliti, ukuba kunokwenzeka ukuphambuka okungentla kuya kubonakala ngakumbi.Isikrini sonyango lwangaphambili, ukutyunyuzwa kunye nokuhluza kwinkqubo yemveli ngokubanzi yi-80 mesh okanye i-100 yesikrini se-mesh, kodwa ngokuqhubela phambili kwezixhobo kunye nobuchwepheshe bezinto ezikrwada, uninzi lwezinto ezikrwada eziye zatyunyuzwa kwi-80 mesh screen kwinkqubo yemveli. ngoku ingadlula i-100. Ubunokwenzeka bento engentla iyancipha kakhulu kwipowder ecocekileyo ethe yachithwa nge-sieve ye-100-mesh.Ngoko ke, ukucokiseka kwezinto eziluhlaza kunye nezincedisi ngokusebenzisa i-100-mesh sieve ngokuthe ngcembe ithatha indawo ye-80-mesh process sieving.

Ubunzima

Ngenxa yokuba ukunyuka okanye ukuncipha kobunzima besixhobo ngasinye kuya kubangela utshintsho olulandelayo kwezinye iimeko zenkqubo, eziya kubangela ukungazinzi komgangatho wamasuntswana, onokubangela uthotho lweengxaki ezifana ne-tablet chipping, i-friability ngokugqithiseleyo, ukuchithwa kancinci okanye ukunciphisa. Unyibiliko, ngoko ngalo lonke ixesha usondla Isixa asikwazi ukulungiswa ngokungekho mthethweni.Kwimeko yeemeko ezizodwa, ubunzima bobunzima kufuneka buqinisekiswe ngokwenkqubo yokuqinisekisa.

Ukulungiswa kwamasuntswana
Kule mihla, igranulator yokuxuba emanzi ngesantya esiphezulu sesona sixhobo sisetyenziswa kakhulu kwimveliso yegranulation.Xa kuthelekiswa nomxubi wemveli kunye negranulator, olu hlobo lwegranulator enyanisweni kungenxa yengxaki yomyalelo owahlukahlukeneyo okanye ukufuna umgangatho ophezulu.Ke ngoko, i-granulator ayipheli, kwaye i-granulator yokuxuba emanzi ngesantya esiphezulu isetyenziswa kuphela njengomxube wendabuko, kwaye ke iigranules ezingaphezulu ezifanayo zifunyenwe ngegranulation.Iimeko zenkqubo ezichaphazela umgangatho we-granules ezimanzi zibandakanya ikakhulu izinto ezininzi ezifana nokushisa, i-dosage, ukongeza indlela ye-binder, isantya esichukumisayo kunye nokusika i-granulator, kunye nexesha lokuvuselela kunye nokusika.

Ubushushu be-adhesive
Ubushushu be-adhesive yi-parameter yesalathisi enzima kakhulu ukulawula kwimveliso ye-scale-up.Kuphantse ukuba akunakwenzeka ukulawula ngokuchanekileyo ukuhambelana kweqondo lokushisa ngaphambi kokufaka i-adhesive rhoqo.Ke ngoko, uninzi lweentlobo aziyi kusebenzisa ubushushu njengesalathiso solawulo, kodwa kwimveliso yokwenyani, kufumaniseka ukuba iqondo lobushushu lesitatshi linefuthe elikhulu kwezinye iindidi ezikhethekileyo.Kwezi ntlobo, iqondo lokushisa kufuneka lifuneke ngokucacileyo.Kwiimeko eziqhelekileyo, ubushushu buphezulu.Ukuphakama kwe-adhesion ephantsi, isezantsi i-friability ye-tablet;Iqondo lokushisa eliphezulu le-starch slurry, i-adhesion ephantsi, kwaye iphezulu yokuchithwa kwethebhulethi.Ngoko ke, kwezinye iinkqubo ezisebenzisa i-starch slurry njenge-binder, ubushushu be-binder kufuneka balawulwe kwinqanaba elithile.

Ubungakanani bokuncamathelisa

Isixa se-binder sinomphumo ocacileyo kakhulu kwiincinci ezimanzi, ngoko ke isixa saso sikwasetyenziswa njengeparameter yokulawula ebalulekileyo.Ngokuqhelekileyo, ubukhulu bexabiso le-binder, buphezulu ubuninzi be-particle kunye nobulukhuni, kodwa isixa se-binder sihlala sihluka kunye nebhetshi yezinto ezikrwada kunye nezincedisayo.Kuya kubakho utshintsho oluncinci kumahluko phakathi kweentlobo ezahlukeneyo, ekufuneka ziqokelelwe kwinkqubo yemveliso yexesha elide ngokweentlobo ezahlukeneyo.Ukulungelelanisa ukuqina kwezinto ezithambileyo, ngaphakathi koluhlu olufanelekileyo, indlela yokwandisa inani le-binder ingcono kunendlela yokwandisa ixesha lokuxuba.

Ukugxilwa kwe-adhesive

Ngokuqhelekileyo, i-concentration enkulu ye-adhesive, i-viscosity enkulu, engenakwahlulwa kwi-dosage yayo.Uninzi lwabavelisi abayi kukhetha ukulungelelanisa ugxininiso xa befumana ugxininiso lwe-adhesive emva kokuqinisekiswa, kodwa lawula izinto ezithambileyo ngokulungelelanisa ubungakanani be-adhesive, ngokuqhelekileyo i-bonding. ayisetyenziselwa ukunyenyisa umgangatho wamasuntswana amanzi, ngoko andiyi kuphinda apha.

Indlela yokongeza i-adhesive

Sebenzisa umatshini wokuxutywa omanzi ngesantya esiphezulu ukwenza igranulate.Ngokuqhelekileyo, kukho iindlela ezimbini zokongeza i-binder.Enye kukumisa umatshini, vula ikhava yegranulator, kwaye ugalele i-binder ngqo.Ngale ndlela, i-binder ayilula ukusabalalisa, kwaye i-granulation ngamanye amaxesha kulula ukubangela ukuxinwa kwendawo ephezulu kunye nokungalingani kwamasuntswana.Umphumo kukuba iipilisi ezikhutshiweyo zichitha okanye zichithe umahluko omkhulu;enye yimeko engayekiyo, usebenzisa i-binder feed hopper, ukuvula ivalve yokutya, kunye nokuvuselela.Ukongeza kwinkqubo, le ndlela yokutya inokuphepha ukungalingani kwendawo kwaye yenza amaqhekeza afane.Nangona kunjalo, ngenxa yeemfuno zohlobo lwe-binder, uyilo lwezixhobo okanye imikhwa yokusebenza, njl., iyanciphisa ukusetyenziswa kwendlela yesibini yokudibanisa kwimveliso.sebenzisa.

Ukukhethwa kwesantya sokuxuba kunye nesantya sokusika

Ukuqulunqwa kwezinto ezithambileyo ngexesha le-granulation kuhambelana ngokuthe ngqo nokukhethwa kwesantya esichukumisayo kunye nokunqunyulwa kwegranulator yokuxuba ngokukhawuleza, enempembelelo enkulu kumgangatho weepellets, kwaye ichaphazela ngokuthe ngqo umgangatho weepilisi ezikhutshiweyo.Okwangoku, i-motor eshukumisayo ye-high-speed emanzi yokuxuba igranulator inezantya ezibini kunye nommiselo wesantya esiguqukayo.Isantya esiphindwe kabini sahlulwe kwisantya esiphantsi kunye nesantya esiphezulu.Ukulawulwa kwesantya sokuguqula isantya sisebenzisa ulawulo lwesantya sencwadi, kodwa ulawulo lwezantya ngesandla luya kuchaphazela amasuntswana kumlinganiselo othile.Ke ngoko, i-granulator yokuxuba isantya esiphezulu kunye nommiselo wesantya sokuguqula isantya ngokubanzi ibeka isantya sokuxuba kunye nexesha lokubaleka, kwaye iqala inkqubo yokusebenza ngokuzenzekelayo ukunciphisa umahluko womntu.Kwiintlobo ngeentlobo, ukuguqulwa kwamaza ombane kusasetyenziswa njengesantya ezibini, kodwa kwiintlobo ezithile ezikhethekileyo, ezisebenza ngaxeshanye, unokonyusa isantya sokufumana imathiriyeli ethambileyo ephakathi, ukuze ugweme ukuxubana kwexesha elide okubangelwa izinto ezithambileyo ziqine kakhulu.

Ukukhetha ukuxuba kunye nexesha lokuqhawula

Ipharamitha yenkqubo echaphazela umgangatho wezinto ezithambileyo lixesha lokuxuba kunye nokuqhawula.Ukumiselwa kweeparameters zayo kugqiba ngokuthe ngqo impumelelo okanye ukungaphumeleli kwenkqubo ye-granulation.Nangona isantya sokuxuba kunye nesantya se-shredding sinokuhlengahlengiswa ngokuguqulwa kwamaxesha amaninzi, ezininzi iinketho zenkqubo zilungisiwe Ukuze kuncitshiswe umahluko, ukuze ufumane izinto ezithambileyo ezifanelekileyo, khetha ukufumana izinto ezithambileyo ezifanelekileyo ngokulungelelanisa ixesha.Ngaphantsi kweemeko eziqhelekileyo, ukuxuba okufutshane kunye nexesha lokuqhawula kuya kunciphisa ubuninzi, ubunzima, kunye nokufana kweengqungquthela, kunye nokuqhekeka kunye nokungafani okungafanelekanga ngexesha lethebhulethi;ixesha elide kakhulu ukuxuba kunye nokutshatyalaliswa kuya kubangela ubuninzi kunye nobunzima beengqungquthela Ukuba kunyuswa, izinto ezithambileyo zingaphumeleli ngexesha lokunyanzeliswa kwethebhulethi, ixesha lokuchithwa kwethebhulethi liya kuba lide, kwaye izinga lokuchithwa liya kuba lifanelekile.

Izixhobo zegranulation kunye nobuchule begranulation
Okwangoku, ukukhethwa kwezixhobo ze-granulating ze-granulation emanzi zihlulwe zibe yi-multi-function granulator kunye ne-swing granulator.Izibonelelo zegranulator yemisebenzi emininzi iphezulu kwaye kulula ukuyisebenzisa kunye nokusetyenziswa.Ukungalungi ngumahluko kwisixa kunye nesantya sokutya ngenxa yokondla ngesandla., Ukufana kwamasuntswana kubi kancinci;i-advanteji yohlobo lwegranulator yojingi kukuba iigranule ziyafana, kwaye umahluko kwisixa sokutya okwenziwa ngesandla kunye nesantya sokutya sincinci.Ukungalungi kukuba ukusebenza kakuhle kuphantsi kwaye ukusetyenziswa kwezikrini ezilahlayo zisetyenziselwa ukuchithwa.Ukufakela akulula kangako.Ubungakanani bamasuntswana angalinganiyo bunokubangela ngokulula ukuba umahluko udlule umda.Inombolo ye-mesh kunye nesantya sesikrini se-particle sonke sinokulawulwa ukuphucula.Ngokubanzi, ukuba amasuntswana amanzi aqinile, unokucinga ngokunyusa isantya, ukukhetha isikrini esikhulu, kunye nokunciphisa ubungakanani bokutya ngexesha ngalinye.Ukuba amasuntswana akhululekile, unokuqwalasela ukunciphisa isantya, ukukhetha isikrini esincinci, kunye nokwandisa ubungakanani bokutya ngexesha ngalinye.Ukongezelela, ekukhethweni kwezikrini, kukho rhoqo izikrini zensimbi ezingenasici kunye nezikrini zenylon ukukhetha kuzo.Ngokwamava okuvelisa kunye neempawu zezinto ezithambileyo, kungcono ukhethe izikrini zensimbi ezingenasici kwizinto ezithambileyo ze-viscous, kunye nezinto ezomileyo ezithambileyo.Isikrini senayiloni sifanelekile ngakumbi, kwaye uhlobo lwegranulator yohlobo lokujingi lungaqwalasela ukuxinana kofakelo lwesikrini ukulungelelanisa ukufumana amasuntswana afanelekileyo.` `

Yomile

I-intuitive embodiment yesiphumo sokumisa ngumswakama we-particle.Ubumanzi besuntswana yinto ebalulekileyo yokuvavanya umgangatho wamasuntswana.Ulawulo olufanelekileyo lwale parameter luchaphazela ngokuthe ngqo ukubonakala kunye nokunyaniseka kwethebhulethi ngexesha lethebhulethi.Ngaphantsi kweemeko eziqhelekileyo, ukuvela kwe-chipboard ngexesha lokubetha kunokuthi kuthathelwe ingqalelo ukuba kubangelwa umswakama ophantsi, kwaye ukuba ukunamathela kwenzeka ngexesha lepilisi, kuyimfuneko ukuqwalasela ukuba kubangelwa umswakama ophezulu.Isalathiso solawulo lokufuma kwamasuntswana ngokuqhelekileyo simiselwa ekuqaleni ngokungqinisisa inkqubo, kodwa ukufuma kudla ngokuba nzima ukuvelisa kwakhona, kwaye kuyimfuneko ukuqokelela idatha kunye nokwenza uluhlu lokulawula ukufuma.Uninzi lweendlela zokomisa zemveli zisebenzisa ukomisa ukubilisa.Izinto ezichaphazelayo ziquka iiparitha zenkqubo ezifana noxinzelelo lwe-steam, ubushushu bokumisa, ixesha lokumisa, kunye nobunzima beengqungquthela ezomileyo.Ubumanzi bamaqhekeza bulawulwa yi-analyzer yomswakama okhawulezayo.Umsebenzisi onobuchule unokuhamba ixesha elide.Kwimveliso yokuvelisa, umxholo wokufuma wento nganye yokomisa ilawulwa ngaphakathi koluhlu olufanelekileyo, olunokuphucula ngokufanelekileyo ukusebenza kwemveliso kwaye inokulawula ngcono umswakama.Ukongeza kumava exesha elide, umthombo wedatha ongundoqo kunye nexesha lokumisa kunye nobushushu bezinto ezomileyo.

I-granulation epheleleyo yeegranule ezomileyo

Okufanayo negranulation emanzi kukuba iiparamitha zenkqubo ezichaphazela umgangatho weegranule ezomileyo ngokubanzi ziyinombolo ye-mesh kunye nesantya sesikrini sonke segranulation.Ukuze uqinisekise imveliso egudileyo ngexesha lethebhulethi, fumana eyona nxalenye ifanelekileyo yokuhanjiswa kwesayizi.Eli lithuba lokugqibela lohlengahlengiso., Ngokukhetha i-meshes eyahlukeneyo kunye nesantya esijikelezayo, kuya kuba nefuthe elibalulekileyo kwiinqununu ezomileyo.Ngokubanzi, xa iincinci ziqinile, khetha isikrini esincinci, kwaye xa iincinci zikhululekile, khetha isikrini esikhulu.Nangona kunjalo, phantsi kweemeko eziqhelekileyo, oku akuyi kuba kukhetho lwenkqubo evuthiweyo.Ukuba ufuna ukufumana amasuntswana angcono, kusafuneka ufunde kwaye uphucule inkqubo yokulungiselela imathiriyeli ethambileyo.

Ukuxuba

Iiparamitha zenkqubo yokuxuba ezichaphazela umgangatho we-particle ngokuqhelekileyo inani lomxube, isantya somxube, kunye nexesha lokuxuba.Isixa somxube sixabiso elimiselweyo emva kokuqinisekiswa kwenkqubo.Isantya somxube sinokuchaphazeleka kukukhukuliseka kwesantya somxube ngenxa yokunxitywa kwezixhobo.Ukufana kokuxuba kufuna ukuhlolwa kwendawo kunye nokuqinisekiswa kwexesha lezixhobo ngaphambi kokuveliswa.Ukuze kuqinisekiswe ukufana kokuxutywa kwamasuntswana ukuya kwinqanaba elikhulu kwaye ufumane iimveliso ezinomgangatho ofanayo, kuyimfuneko ukufumana ixesha lokuxuba ngokuqinisekiswa kwenkqubo.Ixesha elaneleyo lokuxuba liyisiqinisekiso esisebenzayo sokuqinisekisa iqondo lokusasazeka kwe-lubricant kwiincinci ezomileyo, ngaphandle koko i-lubricant iya kwenza amaqela e-electrostatic adsorption ngexesha lokuxuba amaqhekeza omileyo, okuya kuchaphazela umgangatho weengqungquthela.

Ingxelo:
Umxholo weli nqaku uvela kwinethiwekhi yeendaba, eveliswe ngenjongo yokwabelana ngolwazi, njengomxholo wemisebenzi, imiba ye-copyright, nceda uqhagamshelane nathi kwiintsuku ze-30, siya kuqinisekisa kwaye sicime okokuqala.Umxholo wenqaku ungowombhali, awumeli imbono yethu, ayifaki nayiphi na iziphakamiso, kwaye le nkcazo kunye nemisebenzi inenkcazo yokugqibela.